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Newborn Syphilis Cases Still Rising

Syphilis in Newborns Still Rising Despite STI Decline

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In 2024, the number of newborns born with syphilis rose again — marking the 12th consecutive year of increase. Nearly 4,000 cases were reported nationwide, a stark reminder that this entirely preventable condition remains a serious threat.

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Newborn, or congenital, syphilis can lead to devastating outcomes, including miscarriage, stillbirth, and lifelong health complications for babies who survive. Its continued rise reflects serious gaps in prenatal care, STI screening, and timely treatment during pregnancy.

This troubling trend stands in contrast to broader progress. Overall, sexually transmitted infections (STIs) in the U.S. declined by 9% in 2024. Key infections like gonorrhea, chlamydia, and syphilis (in adults) all showed notable drops. But these improvements haven’t yet reached the most vulnerable — unborn children.

Efforts to address the STI crisis must go beyond treating individual infections. Preventing newborn syphilis means ensuring that pregnant people have access to timely testing and care. That includes expanding screening in prenatal visits, improving follow-up for positive cases, and closing treatment gaps — especially in underserved communities.

While the downward trend in overall STI numbers is encouraging, the rising toll of newborn syphilis is a warning. Preventing these tragedies requires stronger coordination across health systems, more targeted public health responses, and a commitment to care that reaches every mother and baby — no matter where they live.

The crisis is not over. But it is still preventable.

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